The Single Best Strategy To Use For daftar naga26
The Single Best Strategy To Use For daftar naga26
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The Khmer people regard themselves as descendants from the nagas and many continue to believe that the nāga exist nowadays, destined to someday return and restore prosperity to their people today.[citation required]
[forty one] ^ While in the Mahavamsa as certainly in the ancient Sanskrit and Pali literature generally, the Nagas are by no means represented as human beings, but as a category of superhuman beings, who inhabited a subterranean world.
need to be significantly distinctive Because the H×H motif with the conclusion of β-stand 1 is replaced by Q×N and thus it is very probable that this enzyme can bind only just one divalent cation inside the Lively internet site.
m values ended up determined from matches of the info into a straight line. Saturation curves demonstrating substrate inhibition had been in shape to equation 2 had been K
provides a maximum catalytic action with one divalent cation bound to the Lively site. These benefits are per the absence of The 2 histidines at the end of β-strand one and the resolve from the x-ray construction of the Zn-NagA that reveals an individual Zn certain to the Mβ-site (21). The apo-enzyme was incubated with 3 equivalents of Fe2+, Mn2+, Ni2+, Cd2+, Co2+ or Zn2+ plus the metal-substituted sorts of NagA have been identified to consist of approximately one equivalent of metallic for each protein subunit following removal of the surplus metallic by passage via a PD-ten column.
The Naga are intriguing beings that straddle the line among the terrestrial along with the divine, embodying mystical powers and profound symbolism. Origins and Cultural Importance
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You'll find a major quantity of problems regarding the mechanism for substrate hydrolysis by NagA which have been unresolved. It is unclear how the divalent cation binds within the active web page of NagA And the way the water molecule is activated for nucleophilic assault on the amide bond. The disparity while in the metal ligation techniques involving the E. coli
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Residues Q59 and N61 had been mutated alongside one another to some set of histidine residues to make an HxH motif that may be analogous to that present in NagA from B. subtilis